biotechnology, business, healthcare, medicine, pharmaceuticals

Dyne’s Investigational DMD Drug DYNE-251 Gets Japan Orphan Drug Status After Strong Trial Data

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Dyne Therapeutics Inc. (NASDAQ: DYN) stands out as one of the best stocks to buy under $20.

On September 29, Dyne Therapeutics announced a significant milestone: Japan’s Ministry of Health, Labour and Welfare (MHLW) has granted Orphan Drug designation for its investigational therapeutic, DYNE-251.

This designation targets individuals with Duchenne muscular dystrophy (DMD) who have mutations in the DMD gene that are amenable to treatment with DYNE-251.

The Orphan Drug status is a crucial step in the development of DYNE-251, potentially providing benefits such as market exclusivity and regulatory assistance, which can accelerate the availability of this promising therapy for patients in need.

Investors and stakeholders will be closely watching Dyne Therapeutics as it advances its pipeline and seeks to address unmet medical needs in the muscular dystrophy community.
https://ca.finance.yahoo.com/news/dyne-investigational-dmd-drug-dyne-205457972.html

college_football, injuries, sports, texas

Parker Livingstone injury update after Texas WR helped off field vs Florida

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Texas football wide receiver Parker Livingstone had to be helped off the field during the Longhorns’ road game against Florida after sustaining an apparent leg injury.

The injury occurred in the second quarter at the conclusion of a 33-yard reception on a second-and-8 play. After catching the pass, Livingstone took a hit to his leg from Florida defensive back Devin Moore. He immediately flipped in the air upon contact and was visibly in pain.

Several Longhorns trainers assisted Livingstone off the field and back to the bench. Once there, he appeared to be limping and showed signs of discomfort.

Before exiting, Livingstone had made his second catch of the game, a reception of at least 14 yards. He currently leads all Texas receivers with two catches for 47 yards, as Texas trails Florida 19-7 in the second quarter.

### Parker Livingstone Injury Update

Livingstone’s leg injury happened near his kneecap area as he made the impressive 33-yard catch downfield. The hit from the Florida defender was significant enough to cause him to flip in the air and forced his early departure from the game.

The Texas medical staff promptly attended to him on the field and helped him back to the sidelines for further evaluation. His status remains uncertain as this story is still developing.

Stay tuned for updates on Parker Livingstone’s condition as more information becomes available.

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https://ca.sports.yahoo.com/news/parker-livingstone-injury-texas-wr-205626556.html

environment, events, public health, technology

IIT Indore Launches TEES Framework For Sustainable Sanitation

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**IIT Indore and BIS Organize National Workshop on Mobile Toilet Management Ahead of Ujjain Simhastha Kumbh 2028**

*Indore (Madhya Pradesh):* In preparation for the Ujjain Simhastha Kumbh 2028, the Indian Institute of Technology Indore (IIT Indore), in collaboration with the Bureau of Indian Standards (BIS), organized a National Workshop on Mobile Toilet Management. The workshop aimed to address strategies for ensuring safe, inclusive, and sustainable sanitation during large-scale religious gatherings.

During the inauguration, Prof. Suhas Joshi, Director of IIT Indore, emphasized that sanitation transcends infrastructure—it embodies human dignity and sustainability. He stated, “With design, technology and governance working together, India can set global benchmarks in public sanitation.”

Sharing insights from his recent visit to Nanyang Technological University (NTU), Singapore, Prof. Joshi highlighted an innovative 3D-printed toilet project that was praised by Prime Minister Narendra Modi. The project exemplifies how innovation can revolutionize sanitation systems in India.

A key highlight of the event was the unveiling of the TEES Framework—Technical, Economic, Environmental, and Social—developed by Assistant Professor Dr. Ashootosh Mandpe from IIT Indore. This framework proposes site-specific, inclusive toilet designs that incorporate features such as ramps for accessibility, solar lighting, smart cleaning alerts, and biogas generation units.

Dr. Mandpe noted, “Our goal is not just to provide sanitation facilities but to build systems that enhance safety, dignity, and trust for every user.”

The workshop brought together over 80 experts from academia, government agencies, and industry, including representatives from IITs, IIM Indore, and CSIR laboratories. Discussions focused on rapid deployment of sanitation facilities, integration of renewable energy, and governance models aligned with BIS standards.

Concluding the event, Prof. Joshi reaffirmed IIT Indore’s commitment to advancing sustainable sanitation solutions and translating research into real-world impact.

**Key Highlights:**

– IIT Indore and BIS hosted a National Workshop on Mobile Toilet Management
– Prof. Suhas Joshi emphasized sanitation as dignity and sustainability
– Assistant Professor Dr. Ashootosh Mandpe presented the TEES Framework
– The framework includes ramps, solar lighting, smart alerts, and biogas units
– Over 80 experts and policymakers participated in the deliberations

*Story by Staff Reporter*
https://www.freepressjournal.in/indore/iit-indore-launches-tees-framework-for-sustainable-sanitation

animal cruelty, animal rights, india, legal action, social issues

Man Forces Dog To Drink Beer In Nagaland, Netizens Demand Strict Action; Video

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A video from Nagaland has gone viral on Instagram and Facebook, showing a middle-aged man forcing an indigenous dog to drink beer. The disturbing footage has left netizens furious, with many demanding immediate action from the police.

In the video, the man can be clearly seen holding the dog’s mouth open and pouring beer down its throat, forcefully closing its mouth afterward. The dog appears visibly distressed, struggling and showing clear signs of discomfort. At one point, it even looks as if the animal is about to vomit due to the taste of the alcohol.

Social media users have overwhelmingly condemned the man’s actions as cruel and inhumane. Many animal lovers expressed shock and disappointment over the lack of empathy shown towards the dog. The incident has sparked a widespread outcry, with calls for swift legal action to hold the responsible individual accountable.

As of now, there have been no reports of any arrest or official action taken against the man.

### Nagaland Rules Against Animal Cruelty

In Nagaland, the Kohima administration has previously issued strict warnings against the killing and maltreatment of animals, including stray dogs. These actions are in adherence to the Prevention of Cruelty to Animals Act. Violators of this act are subject to strict legal consequences under the relevant provisions.

The recent video highlights the need for increased awareness and enforcement of animal protection laws in the region. Authorities are urged to take prompt and decisive measures to prevent such acts of cruelty in the future.
https://www.freepressjournal.in/india/man-forces-dog-to-drink-beer-in-nagaland-netizens-demand-strict-action-video

business, internet, privacy, security, technology

Discord data breach exposes user info, scanned photo IDs

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**Discord Data Breach Exposes User Info, Scanned Photo IDs**
*By Dwaipayan Roy | Oct 04, 2025, 06:21 PM*

Discord, the popular communication platform, has confirmed a data breach involving one of its third-party customer service providers. An “unauthorized party” accessed data from a limited number of users who had contacted Discord’s Customer Support and/or Trust & Safety teams. While the attacker attempted to extort a financial ransom from Discord, they did not gain direct access to the platform itself.

### What Data Was Compromised?
The breach exposed usernames, email addresses, and the last four digits of users’ credit card numbers. Additionally, a small number of government-issued ID photos were accessed. These photos belonged to users who had appealed an age determination on Discord.

Importantly, Discord clarified that full credit card numbers and passwords were **not** affected by this incident. Users whose ID photos were possibly accessed will receive specific notification from Discord.

### Discord’s Response and Security Measures
In response to the breach, Discord has revoked the third-party support provider’s access to its ticketing system and reported the incident to data protection authorities. The company is also working closely with law enforcement agencies to investigate the matter thoroughly.

Furthermore, Discord has conducted a review of its threat detection systems and tightened security controls over its third-party support providers. These steps underscore Discord’s commitment to protecting user data and maintaining trust across its platform.

Users are encouraged to remain vigilant and watch for any communication from Discord regarding this incident. For more updates, stay tuned to official Discord channels.
https://www.newsbytesapp.com/news/science/discord-breach-exposes-user-data-last-4-digits-of-cards/story

business, cricket, entertainment, india, sports

Vidarbha in prime position to win Irani Cup 2025: Details

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**Vidarbha in Prime Position to Win Irani Cup 2025**
*By Rajdeep Saha | Oct 04, 2025 | 07:59 pm*

Vidarbha have put themselves in a commanding position to win the Irani Cup 2025 by setting Rest of India a challenging target of 361 runs. The match is currently underway at the Vidarbha Cricket Association Stadium in Nagpur.

Starting the day at 96 for two, Vidarbha faced some tough bowling from Anshul Kamboj and Saransh Jain. However, crucial contributions from their lower-middle order helped Vidarbha reach a total of 232 in their second innings.

On the bowling front, Rest of India’s attack, led by Kamboj, impressed on Day 4. Kamboj was the standout bowler for ROI, dismantling Vidarbha’s middle order by taking the wickets of batsmen ranked 3 to 6. He finished with remarkable figures of 4 wickets for 34 runs in just 12 overs.

As Rest of India began their chase of 361 runs, early setbacks came their way. Both openers fell before stumps, with Aryan Juyal bowled by Aditya Thakare and Abhimanyu Easwaran trapped lbw by Harsh Dubey. Easwaran scored 17 off 18 deliveries.

At stumps, Rest of India were 30 for 2, with Ishan Kishan (5 not out) and Rajat Patidar (2 not out) holding the crease. They still require 331 runs with eight wickets in hand heading into the final day.

Vidarbha are aiming to clinch their third Irani Cup title in the last decade, having previously won the trophy in the 2017-18 and 2018-19 seasons. Despite being bowled out for 232 in their second innings, their first-innings lead of 128 has provided them with a strong cushion.

Now, with a significant target set and wickets in hand, Rest of India will need a remarkable performance on the final day to stop Vidarbha from lifting their third Irani Cup title.
https://www.newsbytesapp.com/news/sports/roi-in-trouble-against-vidarbha-in-irani-cup/story

chelsea, football, liverpool, premier league, sports

Chelsea v Liverpool: Premier League – live

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Premier League Updates from the 5.30pm BST Kick-Off

⚽ Live scores | Top scorers | Sign up for Football Daily

Arsenal secured a 2-0 victory over West Ham at the Emirates Stadium, moving above Liverpool in the Premier League table, at least for a couple of hours. Here’s how the Premier League standings look right now.

Enzo Maresca on Upcoming Matches

“It’s nice to play Liverpool. It’s a chance to learn and we’ve prepared as best we can,” said Enzo Maresca ahead of the match.

Addressing Chelsea’s injury concerns, Maresca added, “Nine players are unfortunately out, plus we have two or three players carrying injuries. We will try to find solutions and hopefully we can have a good day – for us and for the fans.”

Continue reading for more updates…

https://www.theguardian.com/football/live/2025/oct/04/chelsea-v-liverpool-premier-league-live-score-updates

criminal, health, news, violence

‘Lathi Charge’: Patients Attacked With Stick In Front Of Cops Inside Emergency Ward Of Shamli District Hospital In UP – VIDEO Surfaces

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**Panic Erupts at Shamli District Hospital as Attacker Assaults Patients with Stick**

*Shamli (Uttar Pradesh), October 04:*

A shocking incident unfolded at the District Hospital in Uttar Pradesh’s Shamli when a man attacked two patients admitted in the emergency ward with a lathi (stick) in full view of police officers. The entire episode was caught on camera, and the video is now circulating widely on social media.

The footage shows the attacker barging into the emergency ward carrying a long stick and assaulting the two patients lying on their beds. The injured patients can be seen desperately trying to escape as the assailant swings the stick at them.

According to reports, the incident took place on the night of Thursday, October 2. The victims, identified as brothers Furkan and Irfan, had been admitted to the hospital after being brutally attacked earlier that day following a violent clash with a rival group in Thanabhawan.

While the injured brothers were undergoing emergency treatment, a member of the opposing group stormed into the hospital carrying the lathi and launched a violent attack against them inside the ward. This brazen act exposed serious security lapses at the hospital.

Panic and chaos erupted among patients and staff, but a police officer present in the ward managed to stop the attacker and detain him. However, controversy soon followed as Adarsh Mandi Police Station later denied making any arrest, claiming that the accused had fled the scene. This statement directly contradicts the CCTV footage from inside the hospital.

Authorities have reportedly initiated an investigation into the incident to ascertain the facts and address the security concerns raised by this violent episode.

The attack has raised urgent questions about hospital security and the safety of patients, prompting calls for stricter measures to prevent such incidents in the future.
https://www.freepressjournal.in/india/lathi-charge-patients-attacked-with-stick-in-front-of-cops-inside-emergency-ward-of-shamli-district-hospital-in-up-video-surfaces

international, military, politics

Trump: ‘Hamas must move quickly’ to release hostages ‘or else’

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Trump: ‘Hamas Must Move Quickly’ to Release Hostages ‘Or Else’

US President Donald Trump has urged Hamas to act swiftly in releasing hostages, emphasizing the urgency with the warning, “or else.”

In a recent address, Trump thanked Israel for holding off on continued bombing operations to give the ceasefire deal a chance to succeed. His remarks came during a speech at the UN General Assembly, where he highlighted the importance of de-escalation in the conflict.

Photo Credit: AL DRAGO/REUTERS

By Danielle Greyman-Kennard

https://www.jpost.com/israel-news/article-869387

cricket, india, sports, west indies

‘Been Plaguing For Last Two Series’: Roston Chase Reflects On West Indies’ Batting Struggles After Innings Defeat In IND vs WI 1st Test

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West Indies captain Roston Chase has identified the team’s poor batting performance as the primary reason behind their humiliating defeat in the first Test. “We had a poor batting display. We have not been able to bat for 80 overs. It has been plaguing us for the last two series. We are not getting 250-300 runs,” he admitted.

Reflecting on the decision to bat first after winning the toss, Chase stated that it was not a wrong call. “I don’t think it was a bad decision. It was a good wicket to bat on. We didn’t start well and never put any partnerships in place. That hurt us,” he explained.

Chase also shared the team’s learnings when facing spin bowling in the Test match. “Defence needs to be a bit tighter. It was a wicket that we could bat on. We need to trust our defence and be more solid in it.”

Addressing concerns about the financial challenges impacting West Indies cricket, Chase was candid. “I don’t want to touch too much on it. It’s a struggle in the Caribbean for finances. The system in the Caribbean is a bit poor. The onus is on the players to find some way to get performances,” he remarked.

When asked about the prospects of a revival in West Indies cricket, Chase remained optimistic. “I wouldn’t be a true West Indian if I said no. We have to take some small steps and work towards that. There have been times where other teams have been down and we have been up. So it’s possible,” he added.

Lastly, the West Indies skipper dismissed any suggestions of a lack of desire or motivation within the dressing room. “The guys are eager to play and make an impression and make a living for themselves. So I absolutely don’t see any lack of desire in the dressing room,” he concluded.
https://www.freepressjournal.in/sports/been-plaguing-for-last-two-series-roston-chase-reflects-on-west-indies-batting-struggles-after-innings-defeat-in-ind-vs-wi-1st-test

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